The molecular mechanism of glycation. Harmful effects of advanced glycation end products (AGEs) on the skin

Non-enzymatic glycosylation, commonly known as glycation, is a physiological process that may be intensified by endogenous and exogenous factors. The accumulation of advanced glycation end products (AGEs) effects negatively the aging skin, modifying biochemical, structural, morphological properties skin. study aimed to describe mechanisms AGEs on cells epidermis, dermis, vascular endothelium, well extracellular matrix proteins intercellular lipids. Scientific research being conducted find substances effectively inhibit accompanying glycooxidation.